Current Issue May 2012, Vol. 153, No. 5

Issue Highlights

Commentary

Lower limb pain and locomotor disability This commentary explores the the importance of pain in driving trajectories of disability over time.

Original Research

The effect of changes in lower limb pain on the rate of progression of locomotor disability in middle and old age: Evidence from the NorStOP cohort with 6-year follow-up
Warmth is analgesic in healthy newborns
More educated emergency department patients are less likely to receive opioids for acute pain

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Topical Review

Pain, body, and space: What do patients with complex regional pain syndrome really neglect?

Analgesic antidepressants promote the responsiveness of locus coeruleus neurons to noxious stimulation: Implications for neuropathic pain
16 May 2012
Cristina Alba-Delgado, Juan Antonio Mico, Pilar Sánchez-Blázquez, Esther Berrocoso
TOC summary: The activity of locus coeruleus upon nociceptive stimulation is altered in neuropathic pain conditions, being restored by analgesic antidepressant treatment.Abstract: Antidepressants that...
Hyperalgesia by low doses of the local anesthetic lidocaine involves cannabinoid signaling: An fMRI study in mice
11 May 2012
Simone C. Bosshard, Joanes Grandjean, Aileen Schroeter, Christof Baltes, Hanns U. Zeilhofer, Markus Rudin
Summary: Functional magnetic resonance imaging in wild-type and CB1 receptor knockout mice revealed that lidocaine at low doses induces hyperalgesia, predominantly mediated by CB1 receptors located on...
Estimating the prevalence of chronic pain: validation of recall against longitudinal reporting (the HUNT pain study)
10 May 2012
Tormod Landmark, Pål Romundstad, Ola Dale, Petter C. Borchgrevink, Stein Kaasa
TOC Summary: Pain reporting in the general population is stable, and recall measures of chronic pain may give valid estimates compared with longitudinal recordings.Abstract: Methods for classifying ch...
The influence of children’s pain memories on subsequent pain experience
07 May 2012
Melanie Noel, Christine T. Chambers, Patrick J. McGrath, Raymond M. Klein, Sherry H. Stewart
Summary: Children’s pain memories were a better predictor of subsequent pain reporting than initial reporting. Children with negatively estimated pain memories experienced increased pain over time.Abs...
Risk factors predictive of chronic postsurgical neuropathic pain: The value of the iliac crest bone harvest model
04 May 2012
Valeria Martinez, Skander Ben Ammar, Thierry Judet, Didier Bouhassira, Marcel Chauvin, Dominique Fletcher
Summary: Acute neuropathic characteristics and secondary hyperalgesia are independent, additive factors predictive of chronic postsurgical pain after iliac crest bone harvest.Abstract: Nerve lesions a...

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Publishing Information

PAIN is published by Elsevier for The International Association for the Study of Pain (IASP)

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About PAIN

PAIN is the official journal of The International Association for the Study of Pain® (IASP)). IASP publishes PAIN monthly and each issue includes original research on the nature, mechanisms, and treatment of pain. This peer-reviewed journal provides a forum for the dissemination of research in the basic and clinical sciences of multidisciplinary interest and is cited in Current Contents and Index Medicus.

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Founded in 1973, IASP is the world's largest multidisciplinary organization focused specifically on pain research and treatment. IASP currently has more than 7,500 members from 129 countries and in more than 80 chapters.

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IASP members receive subscriptions to PAIN and Pain: Clinical Updates, as well as reduced registration fees to the World Congress on Pain, members-only pricing on all IASP Press books, and the opportunity to apply for a variety of grants and fellowships available exclusively to IASP members. IASP offers an affordable dues structure that is income-based, with special rates for trainees and retirees.

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