PAIN
Volume 114, Issue 1 , Pages 29-36 , March 2005

Comparison of pain syndromes associated with nervous or somatic lesions and development of a new neuropathic pain diagnostic questionnaire (DN4)

  • Didier Bouhassira

      Affiliations

    • INSERM E-332, AP-HP Hôpital Ambroise Paré, Boulogne and Université Versailles-Saint-Quentin, France
    • Corresponding Author InformationCorresponding author. Address: INSERM E-332, Centre d'Evaluation et de Traitement de la Douleur, CHU Ambroise Paré, 9, avenue Charles de Gaulle, 92100 Boulogne-Billancourt, France. Tel.: +33 1 49 09 45 56; fax: +33 1 49 09 44 35.
    • ,
  • Nadine Attal

      Affiliations

    • INSERM E-332, AP-HP Hôpital Ambroise Paré, Boulogne and Université Versailles-Saint-Quentin, France
    • ,
  • Haiel Alchaar

      Affiliations

    • Centre d'Evaluation et de Traitement de la Douleur, Hôpital Pasteur, Nice, France
    • ,
  • François Boureau

      Affiliations

    • Centre d'Evaluation et de Traitement de la Douleur, Hôpital St Antoine, Paris, France
    • ,
  • Bruno Brochet

      Affiliations

    • Unité de Traitement des Douleurs Chroniques, Fédération des Neurosciences Cliniques, Hôpital Pellegrin, Bordeaux, France
    • ,
  • Jean Bruxelle

      Affiliations

    • Centre d'Evaluation et de Traitement de la Douleur, Hôpital Cochin-Tarnier, Paris, France
    • ,
  • Gérard Cunin

      Affiliations

    • Centre d'Evaluation et de Traitement de la Douleur, Hôpital Lariboisière, Paris, France
    • ,
  • Jacques Fermanian

      Affiliations

    • Service de Biostatistiques, Hôpital Necker, Paris, France
    • ,
  • Patrick Ginies

      Affiliations

    • Hôpital Saint-Eloi, Montpellier, France
    • ,
  • Aurélie Grun-Overdyking

      Affiliations

    • Pfizer Ltd, Paris, France
    • ,
  • Hélène Jafari-Schluep

      Affiliations

    • Pfizer Ltd, Paris, France
    • ,
  • Michel Lantéri-Minet

      Affiliations

    • Centre d'Evaluation et de Traitement de la Douleur, Hôpital Pasteur, Nice, France
    • ,
  • Bernard Laurent

      Affiliations

    • Hôpital de Bellevue, Saint-Etienne, France
    • ,
  • Gérard Mick

      Affiliations

    • Centre d'Etude et Traitement de la Douleur, Hôpital Neurologique, Lyon, France
    • ,
  • Alain Serrie

      Affiliations

    • Centre d'Evaluation et de Traitement de la Douleur, Hôpital Lariboisière, Paris, France
    • ,
  • Dominique Valade

      Affiliations

    • Centre d'Evaluation et de Traitement de la Douleur, Hôpital Lariboisière, Paris, France
    • ,
  • Eric Vicaut

      Affiliations

    • Service de Biophysique, Hôpital Lariboisière, Paris, France

Received 4 June 2004 ,Revised 28 October 2004 ,Accepted 8 November 2004.

References 

  1. Attal N, Bouhassira D. Is there a relationship between symptoms and signs of neuropathic pain? [submitted].
  2. Backonja MM. Defining neuropathic pain. Anesth Analg. 2003;97:785–790
  3. Baron R. Peripheral neuropathic pain: from mechanisms to symptoms. Clin J Pain. 2000;16(Suppl.):S12–S20
  4. Bennett M. The LANSS Pain Scale: the leeds assessment of neuropathic symptoms and signs. Pain. 2001;92:147–157
  5. Bennett GJ. Neuropathic pain: a crisis of definition?. Anesth Analg. 2003;97:619–620
  6. Bouhassira D, Attal N. Novel strategies for neuropathic pain. In: Villanueva L, Dickenson T Ollat H, editors. The pain system in normal and pathological states: a primer for clinicians. IASP press, Seattle, 299–309.
  7. Bouhassira D, Attal N, Fermanian J, Alchaar H, Gautron M, Masquelier E, et al. Development and validation of the neuropathic pain symptom inventory. Pain. 2004;108:248–257
  8. Boureau F, Doubrere JF, Luu M. Study of verbal description in neuropathic pain. Pain. 1990;42:145–152
  9. Dworkin RH. An overview of neuropathic pain: syndromes, symptoms, signs, and several mechanisms. Clin J Pain. 2002;18:343–349
  10. Dworkin RH, Backonja M, Rowbotham MC, Allen RR, Argoff CR, Bennett GJ, et al. Advances in neuropathic pain: diagnosis, mechanisms, and treatment recommendations. Arch Neurol. 2003;60:1524–1534
  11. Galer BS, Jensen MP. Development and preliminary validation of a pain measure specific to neuropathic pain: the Neuropathic Pain Scale. Neurology. 1997;48:332–338
  12. Hansson P. Neuropathic pain: clinical characteristics and diagnostic workup. Eur J Pain. 2002;6:47–50
  13. Hansson P. Difficulties in stratifying neuropathic pain by mechanisms. Eur J Pain. 2003;7:353–357
  14. Jensen TS, Baron R. Translation of symptoms and signs into mechanisms in neuropathic pain. Pain. 2003;102:1–8
  15. Jensen TS, Gottrup H, Sindrup SH, Bach FW. The clinical picture of neuropathic pain. Eur J Pharmacol. 2001;429:1–11
  16. Krause SJ, Backonja M. Development of a neuropathic pain questionnaire. Clin J Pain. 2003;19:306–314
  17. Masson EA, Hunt L, Gem JM, Boulton JM. A novel approach to the diagnosis and assessment of symptomatic diabetic neuropathy. Pain. 1989;38:25–28
  18. Max MB. Is mechanism-based pain treatment attainable? Clinical trials issues. J Pain. 2000;1(Suppl. 1):2–9
  19. Max MB. Clarifying the definition of neuropathic pain. Pain. 2002;96:406–407
  20. Rasmussen PV, Sindrup SH, Jensen TS, Bach FW. Symptoms and signs in patients with suspected neuropathic pain. Pain. 2004;110:461–469
  21. Taube A. Sensitivity, specificity and predictive values: a gaphical approach. Sat Med. 1986;5:585–591
  22. Woolf CJ, Mannion RJ. Neuropathic pain aethiology, symptoms, mechanisms and management. Lancet. 1999;353:1959–1964
  23. Woolf CJ, Max MB. Mechanism-based pain diagnosis: issues for analgesic drug development. Anesthesiology. 2001;95:241–249
  24. Woolf CJ, Bennett GJ, Doherty M, Dubner R, Kidd B, Koltzenburg M, et al. Towards a mechanism-based classification of pain?. Pain. 1998;77:227–229

PII: S0304-3959(04)00579-2

doi: 10.1016/j.pain.2004.12.010

PAIN
Volume 114, Issue 1 , Pages 29-36 , March 2005

Article Tools

* Image Usage & Resolution