PAIN
Volume 118, Issue 1 , Pages 35-42 , November 2005

Prolonged rhythmic gum chewing suppresses nociceptive response via serotonergic descending inhibitory pathway in humans

  • Yuko Mohri

      Affiliations

    • Anesthesiology and Clinical Physiology, Department of Oral Restitution, Division of Oral Health Sciences, Graduate School, Tokyo Medical and Dental University, 1-5-45 Yushima, Bunkyo-ku, Tokyo 113-8549, Japan
    • Department of Physiology, Toho University School of Medicine, 5-21-16 Omori-nishi, Ota-ku Tokyo 143-8540, Japan
  • ,
  • Masaki Fumoto

      Affiliations

    • Department of Physiology, Toho University School of Medicine, 5-21-16 Omori-nishi, Ota-ku Tokyo 143-8540, Japan
  • ,
  • Ikuko Sato-Suzuki

      Affiliations

    • Department of Physiology, Toho University School of Medicine, 5-21-16 Omori-nishi, Ota-ku Tokyo 143-8540, Japan
  • ,
  • Masahiro Umino

      Affiliations

    • Anesthesiology and Clinical Physiology, Department of Oral Restitution, Division of Oral Health Sciences, Graduate School, Tokyo Medical and Dental University, 1-5-45 Yushima, Bunkyo-ku, Tokyo 113-8549, Japan
  • ,
  • Hideho Arita

      Affiliations

    • Department of Physiology, Toho University School of Medicine, 5-21-16 Omori-nishi, Ota-ku Tokyo 143-8540, Japan
    • Corresponding Author InformationCorresponding author. Tel.: +813 3762 2335; fax: +81 3 3762 8148.

Received 29 December 2004 ,Revised 17 June 2005 ,Accepted 18 July 2005.

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PII: S0304-3959(05)00369-6

doi: 10.1016/j.pain.2005.07.009

PAIN
Volume 118, Issue 1 , Pages 35-42 , November 2005