PAIN
Volume 138, Issue 1 , Pages 5-6 , 15 August 2008

Visceral pain and the black box called brain

Received 14 May 2008 ,Accepted 16 May 2008.

References 

  1. Apkarian AV, Bushnell MC, Treede RD, Zubieta JK. Human brain mechanisms of pain perception and regulation in health and disease. Eur J Pain. 2005;9:463–484
  2. Baliki MN, Chialvo DR, Geha PY, Levy RM, Harden RN, Parrish TB, et al. Chronic pain and the emotional brain: specific brain activity associated with spontaneous fluctuations of intensity of chronic back pain. J Neurosci. 2006;26:12165–12173
  3. Casey KL. Forebrain mechanisms of nociception and pain: analysis through imaging. Proc Natl Acad Sci USA. 1999;96:7668–7674
  4. Derbyshire SW. A systematic review of neuroimaging data during visceral stimulation. Am J Gastroenterol. 2003;98:12–20
  5. Iannetti GD, Zambreanu L, Wise RG, Buchanan TJ, Huggins JP, Smart TS. Pharmacological modulation of pain-related brain activity during normal and central sensitization states in humans. Proc Natl Acad Sci USA. 2005;102:18195–18200
  6. Kulkarni B, Bentley DE, Elliott R, Julyan PJ, Boger E, Watson A, et al. Arthritic pain is processed in brain areas concerned with emotions and fear. Arthritis Rheum. 2007;56:1345–1354
  7. Mayer EA, Naliboff BD, Craig AD. Neuroimaging of the brain–gut axis: from basic understanding to treatment of functional GI disorders. Gastroenterology. 2006;131:1925–1942
  8. Neugebauer V, Li W, Bird GC, Han JS. The amygdala and persistent pain. Neuroscientist. 2004;10:221–234
  9. Tagamets MA, Horwitz B. Interpreting PET and fMRI measures of functional neural activity: the effects of synaptic inhibition on cortical activation in human imaging studies. Brain Res Bull. 2001;54:267–273
  10. Wang Z, Bradesi S, Maarek J-MI, Lee K, Winchester WJ, Mayer EA, et al. Regional brain activation in conscious, nonrestrained rats in response to visceral pain. Pain. 2008;138:233–243

PII: S0304-3959(08)00256-X

doi: 10.1016/j.pain.2008.05.011

PAIN
Volume 138, Issue 1 , Pages 5-6 , 15 August 2008

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