PAIN
Volume 139, Issue 2 , Pages 243-247, 15 October 2008

Animal models and the prediction of efficacy in clinical trials of analgesic drugs: A critical appraisal and call for uniform reporting standards

  • Andrew S.C. Rice

      Affiliations

    • Pain Research, Department of Anaesthetics, Pain Medicine and Intensive Care, Faculty of Medicine, Imperial College London, Chelsea & Westminster Hospital Campus, 369 Fulham Road, London SW10 9NH, UK
    • Corresponding Author InformationCorresponding author. Tel.: +44 (0) 208 746 8816; fax: +44 (0) 208 237 5109.
    • ,
  • Dorothy Cimino-Brown

      Affiliations

    • Mari Lowe Centre for Comparative Oncology Research, School of Veterinary Medicine, University of Pennsylvania, 3900 Delancey Street, Philadelphia, PA 19104-6010, USA
    • ,
  • James C. Eisenach

      Affiliations

    • Department of Anesthesia, Wake Forest University School of Medicine, Medical Center Boulevard, Winston Salem, NC 27157, USA
    • ,
  • Vesa K. Kontinen

      Affiliations

    • Department of Anaesthesiology and Intensive Care Medicine, Helsinki University Central Hospital, Helsinki, Finland
    • ,
  • Michael L. Lacroix-Fralish

      Affiliations

    • Department of Psychology, McGill University, 1205 Dr. Penfield Avenue, Montreal, Que., Canada H3A 1B1
    • ,
  • Ian Machin

      Affiliations

    • Pfizer Global Research and Development, Sandwich CT13 9NJ, UK
    • ,
  • (on behalf of the Preclinical Pain Consortium)
    • ,
  • Jeffrey S. Mogil

      Affiliations

    • Department of Psychology, McGill University, 1205 Dr. Penfield Avenue, Montreal, Que., Canada H3A 1B1
    • ,
  • Thomas Stöhr

      Affiliations

    • Bitop AG, Stockumerstr. 28, 58453 Witten, Germany

Received 27 August 2008; accepted 27 August 2008. published online 24 September 2008.

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PII: S0304-3959(08)00508-3

doi:10.1016/j.pain.2008.08.017

PAIN
Volume 139, Issue 2 , Pages 243-247, 15 October 2008

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