Neuroactive steroids inhibit spinal reflex potentiation by selectively enhancing specific spinal GABAA receptor subtypes

Peng, Hsien-Yu; Chen, Gin-Den; Lee, Shin-Da; Lai, Cheng-Yuan; Chiu, Chun-Hsien; Cheng, Chen-Li; Chang, Yu-Shuo; Hsieh, Ming-Chun; Tung, Kwong-Chung; Lin, Tzer-Bin

doi:10.1016/j.pain.2008.12.023

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Volume 143, Issue 1 , Pages 12-20, May 2009

Neuroactive steroids inhibit spinal reflex potentiation by selectively enhancing specific spinal GABA_A receptor subtypes

Hsien-Yu Peng
- Department of Physiology, College of Medicine, Chung-Shan Medical University, No. 110, Chang-Kuo North Rd, Section 1, Taichung 40201, Taiwan
- Department of Veterinary Medicine, College of Veterinary Medicine, National Chung-Hsing University, Taichung, Taiwan
Gin-Den Chen
- Department of Obstetrics and Gynecology, Chung-Shan Medical University Hospital, Chung-Shan Medical University, Taichung, Taiwan
- These two authors contributed equally to this study.
Shin-Da Lee
- School of Physical Therapy, Graduate Institute of Rehabilitation Science, College of Medicine, China Medical University, Taichung, Taiwan
Cheng-Yuan Lai
- Department of Physiology, College of Medicine, Chung-Shan Medical University, No. 110, Chang-Kuo North Rd, Section 1, Taichung 40201, Taiwan
- Department of Veterinary Medicine, College of Veterinary Medicine, National Chung-Hsing University, Taichung, Taiwan
Chun-Hsien Chiu
- Department of Physiology, College of Medicine, Chung-Shan Medical University, No. 110, Chang-Kuo North Rd, Section 1, Taichung 40201, Taiwan
- Department of Veterinary Medicine, College of Veterinary Medicine, National Chung-Hsing University, Taichung, Taiwan
Chen-Li Cheng
- Urology Division, Department of Surgery, Taichung Veterans General Hospital, Taichung, Taiwan
Yu-Shuo Chang
- Department of Physiology, College of Medicine, Chung-Shan Medical University, No. 110, Chang-Kuo North Rd, Section 1, Taichung 40201, Taiwan
Ming-Chun Hsieh
- Department of Physiology, College of Medicine, Chung-Shan Medical University, No. 110, Chang-Kuo North Rd, Section 1, Taichung 40201, Taiwan
Kwong-Chung Tung
- Department of Veterinary Medicine, College of Veterinary Medicine, National Chung-Hsing University, Taichung, Taiwan
Tzer-Bin Lin
- Department of Physiology, College of Medicine, Chung-Shan Medical University, No. 110, Chang-Kuo North Rd, Section 1, Taichung 40201, Taiwan
- Medical Department, Saint Paul’s Hospital, Taoyuan, Taiwan
- Graduate Institute of Biomedical Electronics and Bioinformatics, National Taiwan University, Taipei, Taiwan
- These two authors contributed equally to this study.
- Corresponding author. Address: Department of Physiology, College of Medicine, Chung-Shan Medical University, No. 110, Chang-Kuo North Rd, Section 1, Taichung 40201, Taiwan. Tel.: +886 4 2473 0022; fax: +886 4 2473 9030.