PAIN
Volume 143, Issue 3 , Pages 206-212 , June 2009

Depression-like behaviour in rats with mononeuropathy is reduced by the CB2-selective agonist GW405833

  • Bing Hu

      Affiliations

    • Department of CNS Research, Boehringer Ingelheim Pharma GmbH & Co. KG, Birkendorfer Straße 65, 88397 Biberach an der Riss, Germany
    • ,
  • Henri Doods

      Affiliations

    • Department of CNS Research, Boehringer Ingelheim Pharma GmbH & Co. KG, Birkendorfer Straße 65, 88397 Biberach an der Riss, Germany
    • ,
  • Rolf-Detlef Treede

      Affiliations

    • Chair of Neurophysiology, Center for Biomedicine and Medical Technology Mannheim (CBTM), Ruprecht-Karls-University Heidelberg, Ludolf-Krehl-Straße 13-17, 68167 Mannheim, Germany
    • ,
  • Angelo Ceci

      Affiliations

    • Department of CNS Research, Boehringer Ingelheim Pharma GmbH & Co. KG, Birkendorfer Straße 65, 88397 Biberach an der Riss, Germany
    • Corresponding Author InformationCorresponding author. Tel.: +49 7351 54 7558.

Received 7 November 2008 ,Revised 16 February 2009 ,Accepted 20 February 2009.

References 

  1. Attal N, Cruccu G, Haanpää M, Hansson P, Jensen TS, Nurmikko T, et al. EFNS guidelines on pharmacological treatment of neuropathic pain. Eur J Neurol. 2006;13:1153–1169
  2. Bair MJ, Robinson RL, Katon W, Kroenke K. Depression and pain comorbidity: a literature review. Arch Intern Med. 2003;163:2433–2445
  3. Bennett GJ, Xie YK. A peripheral mononeuropathy in rat that produces disorders of pain sensation like those seen in man. Pain. 1988;33:87–107
  4. Bernard JF, Huang GF, Besson JM. Effect of noxious somesthetic stimulation on the activity of neurons of the nucleus centralis of the amygdala. Brain Res. 1990;523:347–350
  5. Bernard JF, Bester H, Besson JM. Involvement of the spino-parabrachio-amydaloid and hypothalamic pathways in the autonomic and affective emotional aspects of pain. Prog Brain Res. 1996;107:243–255
  6. Cryan JF, Markou A, Lucki I. Assessing antidepressant activity in rodents: recent developments and future needs. Trends Pharmacol Sci. 2002;23:238–245
  7. Detke MJ, Rickels M, Lucki I. Active behaviors in the rat forced swimming test differentially produced by serotonergic and noradrenergic antidepressants. Psychopharmacology. 1995;121:66–72
  8. Dickens C, McGowan L, Dale S. Impact of depression on experimental pain perception: a systematic review of the literature with meta-analysis. Psychosom Med. 2003;65:369–375
  9. Dowdall T, Robinson I, Meert TF. Comparison of five different rat models of peripheral nerve injury. Pharmacol Biochem Behav. 2005;80:93–108
  10. Dworkin RH, Gitlin MJ. Clinical aspects of depression in chronic pain patients. Clin J Pain. 1991;17:79–94
  11. Dworkin RH, O’Connor AB, Backonja M, Farrar JT, Finnerup NB, Jensen TS, et al. Pharmacologic management of neuropathic pain: evidence-based recommendations. Pain. 2007;132:237–251
  12. Fishbain DA. Approaches to treatment decisions for psychiatric comorbidity in the management of the chronic pain patient. Med Clin North Am. 1999;83:737–760
  13. Forde G. Adjuvant analgesics for the treatment of neuropathic pain: evaluation efficacy and safety profile. J Fam Pract. 2007;3–12
  14. Gonçalves L, Silva R, Pinto-Riberio F, Pêgo F, Bessa JM, Pertovaara A, et al. Neuropathic pain is associated with depressive behaviour and induces neuroplasticity in the amigdala of the rat. Exp Neurol. 2008;213:48–56
  15. Gordon DB. Nonopioid and adjuvant analgesics in chronic pain management: strategies for effective use. Nun Clin North Am. 2003;38:447–464
  16. Kontinen VK, Kauppila T, Paananen S, Pertovaara A, Kalso E. Behavioural measures of depression and anxiety in rats with spinal nerve ligation-induced neuropathy. Pain. 1999;80:341–346
  17. Knotkova H, Pappagallo M. Adjuvant analgesics. Anesthesiol Clin. 2007;25:775–786
  18. Leino P, Magni G. Depressive and distress symptoms as predictors of low back pain, neck–shoulder pain, and other musculoskeletal morbidity: a 10-year follow-up of metal industry employees. Pain. 1993;53:89–94
  19. Lépine JP, Briley M. The epidemiology of pain in depression. Hum Psychopharmacol. 2004;19:S3–S7
  20. Leventhal L, Smith V, Hornby G, Andree TH, Brandt MR, Rogers KE. Differential and synergistic effects of selective norepinephrine and serotonin reuptake inhibitors in rodent models of pain. J Pharmacol Exp Ther. 2007;320:1178–1185
  21. Lucki I. The forced swimming test as a model for core and component behavioral effects of antidepressant drugs. Behav Pharmacol. 1997;8:523–532
  22. Magni G, Marchetti M, Moreschi C, Merskey H, Luchini SR. Chronic musculoskeletal pain and depressive symptoms in the National Health and Nutrition Examination. Epidemiologic Follow-up Study. Pain. 1993;53:163–168
  23. Magni G, Moreschi C, Rigatti-Luchini S, Merskey H. Prospective Study on the relationship between depressive symptoms and chronic musculoskeletal pain. Pain. 1994;56:289–297
  24. Melzack R. From the gate to the neuromatrix. Pain. 1999;S121–S126
  25. McGeeney BE. Adjuvant agents in cancer pain. Clin J Pain. 2008;24:S14–S20
  26. Micó JA, Ardid D, Berrocoso E, Eschalier A. Antidepressant and pain. Trends Pharmacol Sci. 2006;22:348–354
  27. Möller KÄ, Johansoon B, Berge OG. Assessing mechanical allodynia in the rat paw with a new electronic algometer. J Neurosci. 1998;84:41–47
  28. Rice ASC, Hill RG. New treatment of neuropathic pain. Annu Rev Med. 2006;57:535–541
  29. Rice ASC, Cimino-Brown D, Eisenach JC, Kontinen VS, Lacroix-Fralish ML, Machin I, et al. Animal model and the prediction of efficacy in clinical trials of analgesics drugs: a critical appraisal and call for uniform reporting standards. Pain. 2008;139:243–247
  30. Rizvi TA, Ennis M, Behbehmi MM, Shipley MT. Connections between the central nucleus of the amygdala and the midbrain periaqueductal gray: topography and reciprocity. J Comp Neurol. 1991;303:121–131
  31. Roeska K, Doods H, Arndt K, Treede RD, Ceci A. Anxiety-like behaviour in rats with mononeuropathy is reduced by the analgesic drugs morphine and gabapentin. Pain. 2008;139:349–357
  32. Rolke R, Magel W, Campbell KA, Schalber C, Caspari S, Birklein F, et al. Quantitative sensory testing: a comprehensive protocol for clinical trials. Eur J Pain. 2006;10:77–88
  33. Shir Y, Zeltser R, Vatine JJ, Carmi G, Belfer I, Zangen A, et al. Correlation of intact sensibility and neuropathic pain-related behaviors in eight inbred and outbred rat strains and selection lines. Pain. 2001;90:75–82
  34. Sindrup SH, Jensen TS. Efficacy of pharmacological treatments of neuropathic pain: an update and effect related to mechanism of drug action. Pain. 1999;83:389–400
  35. Sindrup SH, Jensen TS. Pharmacology treatment of pain in polyneuropathy. Neurology. 2000;55:915–920
  36. Suzuki T, Amata M, Sakaue G, Nishmura S, Inoue T, Shibata M, et al. Experimental neuropathy in mice is associated with delayed behavioural changes related to anxiety and depression. Anesth Analg. 2007;104:1570–1577
  37. Tunks ER, Crook J, Weir R. Epidemiology of chronic pain with psychological comorbidity: prevalence, risk, course, and prognosis. Can J Psychiatry. 2008;53:224–234
  38. Van Bockstaele EJ, Chan J, Pickel VM. Input from central nucleus of the amygdala efferents to pericoerulear dendrites, some of which contain tyrosine hydroxylase immunoreactivity. J Neurosci Res. 1996;45:289–302
  39. Vivancos GC, Verri WA, Cunha TM, Schivo IRS, Parada CA, Cunha FQ, et al. An electronic pressure-meter nociceptive paw test for rats. Braz J Med Biol Res. 2004;37:391–399
  40. Whiteside GT, Gottshall SL, Boulet JM, Chaffer SM, Harrison JE, Pearson MS, et al. A role for cannabinoid receptors, but not endogenous opioids, in the antinociceptive activity of the CB2-selective agonist, GW405833. Eur J Pharmacol. 2005;528:65–72
  41. Zeng Q, Wang S, Lim G, Yang L, Mao J, Sung B, et al. Exacerbated mechanical allodynia in rats with depression-like behaviour]. Brain Res. 2008;1200:27–38
  42. Zimmerman M. Ethical guidelines for investigations of experimental pain in conscious animals. Pain. 1983;16:109–110

PII: S0304-3959(09)00135-3

doi: 10.1016/j.pain.2009.02.018

PAIN
Volume 143, Issue 3 , Pages 206-212 , June 2009

Article Tools

* Image Usage & Resolution