PAIN
Volume 143, Issue 3 , Pages 161-162 , June 2009

Diffuse Noxious Inhibitory Control (DNIC) as a tool for exploring dysfunction of endogenous pain modulatory systems

Received 5 March 2009 ,Accepted 5 March 2009.

References 

  1. Bouhassira D, Danziger N, Attal N, Guirimand F. Comparison of the pain suppressive effects of clinical and experimental painful conditioning stimuli. Brain. 2003;126:1068–1078
  2. Craig AD. A new view of pain as a homeostatic emotion. TINS. 2003;26:303–307
  3. De Broucker T, Cesaro P, Willer JC, Le Bars D. Diffuse Noxious Inhibitory Controls (DNIC) in man: involvement of a spino-reticular tract. Brain. 1990;113:1223–1234
  4. Dickenson AH, Suzuki R, Matthews EA, Rahman W, Urch C, Seagrove L, et al. Balancing excitations and inhibitions in spinal circuits. In:  Villanueva L,  Dickenson AH,  Ollat H editor. The pain system in normal and pathological states: a primer for clinicians. Seattle: IASP Press; 2004;p. 79–106
  5. Goffaux P, Redmond WJ, Rainville P, Marchand S. Descending analgesia-when the spine echoes what the brain expects. Pain. 2007;130:137–143
  6. King CD, Wong F, Currie T, Mauderli AP, Fillingim RB, Riley JL. Deficiency in endogenous modulation of prolonged heat pain in patients with Irritable Bowel Syndrome and Temporomandibular Disorder. Pain. 2009;143:172–178
  7. Le Bars D, Dickenson AH, Besson JM. Diffuse noxious inhibitory controls (DNIC): I. Effects on dorsal horn convergent neurones in the rat. Pain. 1979;6:283–304
  8. Schweinhardt P, Sauro KM, Bushnell MC. Fibromyalgia: a disorder of the brain?. Neuroscientist. 2008;14:415–421
  9. Villanueva L, Bouhassira D, Le Bars D. The medullary subnucleus reticularis dorsalis (SRD) as a key link in both the transmission and modulation of pain signals. Pain. 1996;67:231–240
  10. Villanueva L, Fields H. Endogenous central mechanisms of pain modulation. In:  Villanueva L,  Dickenson AH,  Ollat H editor. The pain system in normal and pathological states: a primer for clinicians. Seattle: IASP Press; 2004;p. 223–243
  11. Wall PD. Pain in context: the intellectual roots of pain research and therapy. In: Devor M, Wiesenfeld-Hallin Z, Rowbotham MC, editors. Proceedings of the 9th world congress on pain. Seattle: IASP Press; 1999. p. 19–33.

PII: S0304-3959(09)00153-5

doi: 10.1016/j.pain.2009.03.003

PAIN
Volume 143, Issue 3 , Pages 161-162 , June 2009