PAIN
Volume 147, Issue 1 , Pages 9-10 , 15 December 2009

Etifoxine (Stresam®) for chemotherapy-induced pain?

Received 29 August 2009 ,Accepted 18 September 2009.

References 

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  2. Cata JP, Weng HR, Lee BN, Reuben JM, Dougherty PM. Clinical and experimental findings in humans and animals with chemotherapy-induced peripheral neuropathy. Minerva Anestesiol. 2006;72:151–169
  3. Coull JA, Boudreau D, Bachand K, Prescott SA, Nault F, Sik A, et al. Trans-synaptic shift in anion gradient in spinal lamina I neurons as a mechanism of neuropathic pain. Nature. 2003;424:938–942
  4. Girard C, Liu S, Cadepond F, Adams D, Lacroix C, Verleye M, et al. Etifoxine improves peripheral nerve regeneration and functional recovery. Proc Natl Acad Sci USA. 2008;105:20505–20510
  5. Hamon A, Morel A, Hue B, Verleye M, Gillardin JM. The modulatory effects of the anxiolytic etifoxine on GABAa receptors are mediated by the beta subunit. Neuropharmacology. 2003;45:293–303
  6. Hearn J, Higginson IJ. Cancer pain epidemiology: a systematic review. In:  Bruera ED,  Portenoy RK editor. Cancer pain-assenssment and management. Cambridge: Cambridge University Press; 2003;p. 19–37
  7. Knabl J, Witschi R, Hösl K, Reinold H, Zeilhofer UB, Ahmadi S, et al. Reversal of pathological pain through specific spinal GABAa receptor subtypes. Nature. 2008;451:330–334
  8. Papadopoulos V, Baraldi M, Guilarte TR, Knudsen TB, Lacapere JJ, Lindemann P, et al. Translocator protein (18kDa): new nomenclature for the peripheral-type benzodiazepine receptor based on its structure and molecular function. Trends Pharmacol Sci. 2006;27:402–409
  9. Schlichter R, Rybalchenko V, Poisbeau P, Verleye M, Gillardin J. Modulation of GABAergic synaptic transmission by the non-benzodiazepine anxiolytic etifoxine. Neuropharmacology. 2000;39:1523–1535

PII: S0304-3959(09)00557-0

doi: 10.1016/j.pain.2009.09.021

PAIN
Volume 147, Issue 1 , Pages 9-10 , 15 December 2009

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