PAIN
Volume 149, Issue 1 , Pages 5-6 , April 2010

Commentary: A burning question of subgroup analysis in pain trials

Received 7 January 2010 ,Accepted 13 January 2010.

References 

  1. Adams KF. Post hoc subgroup analysis and the truth of a clinical trial. Am Heart J. 1998;136:753–758
  2. Fields HL, Rowbotham M, Baron R. Postherpetic neuralgia: irritable nociceptors and deafferentation. Neurobiol Dis. 1998;5:209–227
  3. Formaker BK, Frank ME. Taste function in patients with oral burning. Chem Senses. 2000;25:575–581
  4. Grémeau-Richard C, Dubray C, Aublet-Cuvelier B, Ughetto S, Woda A. Effect of lingual nerve block on burning mouth syndrome (somatodynia): A randomized crossover trial. Pain. 2010;149:27–32
  5. Grushka M, Sessle BJ, Howley TP. Psychophysical assessment of tactile, pain and thermal sensory functions in burning mouth syndrome. Pain. 1987;28:169–184
  6. Hagelberg N, Forssell H, Rinne JO, Scheinin H, Taiminen T, Aalto S, et al. Striatal dopamine D1 and D2 receptors in burning mouth syndrome. Pain. 2003;101:149–154
  7. Jaaskelainen SK, Forssell H, Tenovuo O. Abnormalities of the blink reflex in burning mouth syndrome. Pain. 1997;73:455–460
  8. Jaaskelainen SK, Rinne JO, Forssell H, Tenovuo O, Kaasinen V, Sonninen P, et al. Role of the dopaminergic system in chronic pain – a fluorodopa-PET study. Pain. 2001;90:257–260
  9. Lauria G, Majorana A, Borgna M, Lombardi R, Penza P, Padovani A, et al. Trigeminal small-fiber sensory neuropathy causes burning mouth syndrome. Pain. 2005;115:332–337
  10. Petersen KL, Fields HL, Brennum J, Sandroni P, Rowbotham MC. Capsaicin evoked pain and allodynia in post-herpetic neuralgia. Pain. 2000;88:125–133
  11. Scholz J, Woolf CJ. Can we conquer pain?. Nat Neurosci. 2002;5:1062–1067
  12. Svensson P, Bjerring P, Arendt-Nielsen L, Kaaber S. Sensory and pain thresholds to orofacial argon laser stimulation in patients with chronic burning mouth syndrome. Clin J Pain. 1993;9:207–215
  13. Yilmaz Z, Renton T, Yiangou Y, Zakrzewska J, Chessell IP, Bountra C, et al. Burning mouth syndrome as a trigeminal small fibre neuropathy: increased heat and capsaicin receptor TRPV1 in nerve fibres correlates with pain score. J Clin Neurosci. 2007;14:864–871

PII: S0304-3959(10)00032-1

doi: 10.1016/j.pain.2010.01.010

PAIN
Volume 149, Issue 1 , Pages 5-6 , April 2010

Article Tools