PAIN
Volume 150, Issue 3 , Pages 550-560 , September 2010

Microglial/macrophage GRK2 determines duration of peripheral IL-1β-induced hyperalgesia: Contribution of spinal cord CX3CR1, p38 and IL-1 signaling

  • Hanneke L.D.M. Willemen

      Affiliations

    • Laboratory of Neuroimmunology and Developmental Origins of Disease (NIDOD), University Medical Center Utrecht, 3584 EA Utrecht, The Netherlands
    • These authors contributed equally to this work.
    • ,
  • Niels Eijkelkamp

      Affiliations

    • Laboratory of Neuroimmunology and Developmental Origins of Disease (NIDOD), University Medical Center Utrecht, 3584 EA Utrecht, The Netherlands
    • Integrative Immunology and Behavior Program, College of ACES and College of Medicine, University of Illinois at Urbana-Champaign, Urbana, IL 61801, USA
    • These authors contributed equally to this work.
    • ,
  • Huijing Wang

      Affiliations

    • Laboratory of Neuroimmunology and Developmental Origins of Disease (NIDOD), University Medical Center Utrecht, 3584 EA Utrecht, The Netherlands
    • ,
  • Robert Dantzer

      Affiliations

    • Integrative Immunology and Behavior Program, College of ACES and College of Medicine, University of Illinois at Urbana-Champaign, Urbana, IL 61801, USA
    • ,
  • Gerald W. Dorn II

      Affiliations

    • Center for Pharmacogenomics, Washington University, St. Louis, MI 63110, USA
    • ,
  • Keith W. Kelley

      Affiliations

    • Integrative Immunology and Behavior Program, College of ACES and College of Medicine, University of Illinois at Urbana-Champaign, Urbana, IL 61801, USA
    • ,
  • Cobi J. Heijnen

      Affiliations

    • Laboratory of Neuroimmunology and Developmental Origins of Disease (NIDOD), University Medical Center Utrecht, 3584 EA Utrecht, The Netherlands
    • Integrative Immunology and Behavior Program, College of ACES and College of Medicine, University of Illinois at Urbana-Champaign, Urbana, IL 61801, USA
    • ,
  • Annemieke Kavelaars

      Affiliations

    • Laboratory of Neuroimmunology and Developmental Origins of Disease (NIDOD), University Medical Center Utrecht, 3584 EA Utrecht, The Netherlands
    • Integrative Immunology and Behavior Program, College of ACES and College of Medicine, University of Illinois at Urbana-Champaign, Urbana, IL 61801, USA
    • Corresponding Author InformationCorresponding author at: Laboratory for Neuroimmunology and Developmental Origins of Disease, University Medical Center Utrecht, Lundlaan 6, Office KC 03.068.0, 3584 EA Utrecht, The Netherlands. Tel.: +31 88 755 4359; fax: +31 88 755 5311.

Received 19 January 2010 ,Revised 17 May 2010 ,Accepted 15 June 2010.

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PII: S0304-3959(10)00360-X

doi: 10.1016/j.pain.2010.06.015

PAIN
Volume 150, Issue 3 , Pages 550-560 , September 2010

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