« Previous
Next »
PAIN
Volume 151, Issue 2
, Pages 506-515
, November 2010
Direct blockade of inflammatory hypernociception by peripheral A1 adenosine receptors: Involvement of the NO/cGMP/PKG/KATP signaling pathway
References
- . Effects of (−)-N6-(R-phenylisopropyl)-adenosine (PIA) and caffeine on nociception and morphine-induced analgesia, tolerance and dependence in mice. Eur J Pharmacol. 1985;112:171–179
- . Opioid and adenosine peripheral antinociception are subject to tolerance and withdrawal. J Neurosci. 1995;15:8031–8038
- . Multiple receptors involved in peripheral alpha 2, mu, and A1 antinociception, tolerance, and withdrawal. J Neurosci. 1997;17:735–744
- . Adenosine A1 receptor antisense infused in striatum of rats: actions on alcohol-induced locomotor impairment, blood alcohol, and body temperature. Alcohol. 1997;14:617–621
- . Observations on the algogenic actions of adenosine compounds on the human blister base preparation. Pain. 1977;3:367–377
- . Formalin-induced pain and mu-opioid receptor density in brain and spinal cord are modulated by A1 and A2a adenosine agonists in mice. Brain Res. 2002;956:339–348
- . Distinct subsets of unmyelinated primary sensory fibers mediate behavioral responses to noxious thermal and mechanical stimuli. Proc Natl Acad Sci USA. 2009;106:9075–9080
- . Cytokine-mediated inflammatory hyperalgesia limited by interleukin-4. Br J Pharmacol. 1999;126:45–50
- . Cytokine-mediated inflammatory hyperalgesia limited by interleukin-1 receptor antagonist. Br J Pharmacol. 2000;130:1418–1424
- . Morphine peripheral analgesia, depends on activation of the PI3Kgamma/AKT/nNOS/NO/KATP signaling pathway. Proc Natl Acad Sci USA. 2010;107:4442–4447
- . The antinociceptive effects of the systemic adenosine A1 receptor agonist CPA in the absence and in the presence of spinal cord sensitization. Pharmacol Biochem Behav. 2005;82:721–726
- . Spinal adenosine modulates descending antinociceptive pathways stimulated by morphine. J Pharmacol Exp Ther. 1986;239:88–93
- . Complex role of peripheral adenosine in the genesis of the response to subcutaneous formalin in the rat. Eur J Pharmacol. 1995;281:311–318
- . The role and regulation of adenosine in the central nervous system. Annu Rev Neurosci. 2001;24:31–55
- . Release of two vasodilators, adenosine and prostacyclin, from isolated rabbit hearts during controlled hypoxia. J Physiol. 1983;340:487–501
- . Intrathecal, but not intravenous adenosine reduces allodynia in patients with neuropathic pain. Pain. 2003;105:65–70
- . Adenosine: an old drug newly discovered. Anesthesiology. 2009;111:904–915
- . Prostaglandins, aspirin-like drugs and analgesia. Nat New Biol. 1972;240:200–203
- . The molecular mechanism of action of peripheral morphine analgesia: stimulation of the cGMP system via nitric oxide release. Eur J Pharmacol. 1991;201:121–122
- . I – prostaglandin hyperalgesia, a cAMP/Ca2+ dependent process. Prostaglandins. 1979;18:179–190
- . Teleantagonism: a pharmacodynamic property of the primary nociceptive neuron. Proc Natl Acad Sci USA. 2008;105:19038–19043
- . Adenosine A1 receptors mediate local anti-nociceptive effects of acupuncture. Nat Neurosci. 2010;13:883–888
- . Systemic adenosine infusions alleviated neuropathic pain. Pain. 2001;94:121–122
- . Phase 2, double-blind, placebo-controlled, dose-response trial of intravenous adenosine for perioperative analgesia. Anesthesiology. 2008;109:1085–1091
- . The molecular dynamics of pain control. Nat Rev Neurosci. 2001;2:83–91
- . Peptide- and non-peptide-containing unmyelinated primary afferents: the parallel processing of nociceptive information. Philos Trans R Soc Lond B Biol Sci. 1985;308:283–289
- . Endocannabinoid metabolism and uptake: novel targets for neuropathic and inflammatory pain. Br J Pharmacol. 2007;152:624–632
- . Hyperalgesia, anxiety, and decreased hypoxic neuroprotection in mice lacking the adenosine A1 receptor. Proc Natl Acad Sci USA. 2001;98:9407–9412
- . Exogenous and endogenous adenosine enhance the spinal antiallodynic effects of morphine in a rat model of neuropathic pain. Pain. 1999;80:31–36
- . Pharmacology of the spinal adenosine receptor which mediates the antiallodynic action of intrathecal adenosine agonists. J Pharmacol Exp Ther. 1996;277:1642–1648
- . Cytokine-mediated inflammatory hyperalgesia limited by interleukin-13. Eur Cytokine Network. 2001;12:260–267
- . Intravenous adenosine alleviates neuropathic pain: a double blind placebo controlled crossover trial using an enriched enrolment design. Pain. 2003;103:111–117
- . High adenosine plasma concentration as a prognostic index for outcome in patients with septic shock. Crit Care Med. 2000;28:3198–3202
- . A method to perform direct transcutaneous intrathecal injection in rats. J Pharmacol Toxicol Methods. 1994;32:197–200
- . Characterization of adenosine receptors mediating spinal sensory transmission related to nociceptive information in the rat. Anesthesiology. 1997;87:577–584
- . Role of ATP-sensitive K+ channels in antinociception induced by R-PIA, an adenosine A1 receptor agonist. Naunyn Schmiedebergs Arch Pharmacol. 1994;350:57–62
- . Peripheral neuronal nitric oxide synthase activity mediates the antinociceptive effect of Crotalus durissus terrificus snake venom, a delta- and kappa-opioid receptor agonist. Life Sci. 2004;75:559–573
- . Cytokine-mediated inflammatory hyperalgesia limited by interleukin-10. Br J Pharmacol. 1995;115:684–688
- . Antinociception by adenosine analogs and inhibitors of adenosine metabolism in an inflammatory thermal hyperalgesia model in the rat. Pain. 1998;74:235–245
- . Antinociceptive effects in mice after intrathecal injection of 5′-N-ethylcarboxamide adenosine. Neurosci Lett. 1984;51:325–330
- . Analgesic effect of adenosine on ischaemic pain in human volunteers. Br J Anaesth. 1999;82:427–428
- . The peripheral antinociceptive effect induced by morphine is associated with ATP-sensitive K(+) channels. Br J Pharmacol. 2000;129:110–114
- . Peripheral analgesic blockade of hypernociception: activation of arginine/NO/cGMP/protein kinase G/ATP-sensitive K+ channel pathway. Proc Natl Acad Sci USA. 2004;101:3680–3685
- . Pharmacokinetic/pharmacodynamic modelling of the, anti-hyperalgesic and anti-nociceptive effect of adenosine A1 receptor partial agonists in neuropathic pain. Eur J Pharmacol. 2005;514:131–140
- . Distribution of antinociceptive adenosine A1 receptors in the spinal cord dorsal horn and relationship to primary afferents and neuronal subpopulations. Neuroscience. 2003;121:907–916
- . Antinociceptive effect of perioperative adenosine infusion in abdominal hysterectomy. Acta Anaesthesiol Scand. 1997;41:473–479
- . Efficacy of intrathecal adenosine for postoperative pain relief. Eur J Anaesthesiol. 2006;23:449–453
- . Adenosine reduces secondary hyperalgesia in two human models of cutaneous inflammatory pain. Anesth Analg. 1999;88:605–610
- . Intrathecal and systemic R-phenylisopropyl-adenosine reduces scratching behavior in a rat mononeuropathy model. Neuroreport. 1996;7:1856–1860
- . Activation of ATP-sensitive K(+) channels: mechanism of peripheral antinociceptive action of the nitric oxide donor, sodium nitroprusside. Eur J Pharmacol. 2000;400:67–71
- . Systemic adenosine infusion: a new treatment modality to alleviate neuropathic pain. Pain. 1995;61:155–158
- . Ecto-5′-nucleotidase (CD73) inhibits nociception by hydrolyzing AMP to adenosine in nociceptive circuits. J Neurosci. 2010;30:2235–2244
- . Opioid receptors on peripheral sensory neurons. Adv Exp Med Biol. 2003;521:69–76
- . Adenosine receptors. J Biol Chem. 1992;267:6451–6454
- . Direct cutaneous hyperalgesia induced by adenosine. Neuroscience. 1990;38:757–762
- . Fructose-1,6-bisphosphate reduces, inflammatory pain-like behaviour in mice: role of adenosine acting on A1 receptors. Br J Pharmacol. 2009;158:558–568
- . Hypernociceptive role of cytokines and chemokines targets for analgesic drug development. Pharmacol Ther. 2006;112:116–138
- . An electronic pressure-meter nociception paw test for rats. Braz J Med Biol Res. 2004;37:391–399
- . Brain adenosine concentration during hypoxia in rats. Am J Physiol. 1981;241:H235–H242
- . Nociceptors – noxious stimulus detectors. Neuron. 2007;55:353–364
- . Increased nociceptive response in mice lacking the adenosine A1 receptor. Pain. 2005;113:395–404
- . Adenosine A1 but not A2a receptor agonist reduces hyperalgesia caused by a surgical incision in rats: a pertussis toxin-sensitive G protein-dependent process. Anesthesiology. 2007;107:797–806
- . Molecular cloning and characterization of an adenosine receptor: the A3 adenosine receptor. Proc Natl Acad Sci USA. 1992;89:7432–7436
- . Ethical guidelines for investigations of experimental pain in conscious animals. Pain. 1983;16:109–110
- . Topographically distinct epidermal nociceptive circuits revealed by axonal tracers targeted to Mrgprd. Neuron. 2005;45:17–25
PII: S0304-3959(10)00482-3
doi: 10.1016/j.pain.2010.08.014
© 2010 International Association for the Study of Pain. Published by Elsevier Inc. All rights reserved.
« Previous
Next »
PAIN
Volume 151, Issue 2
, Pages 506-515
, November 2010

