Current Issue February 2012, Vol. 153, No. 2

Issue Highlights

Commentary

How does topical lidocaine relieve pain? These findings raise broad questions about the primary afferent mechanisms that contribute to neuropathic pain.

Original Research

Lidocaine patch (5%) produces a selective, but incomplete block of Ad and C fibers
Partial medial meniscectomy produces osteoarthritis pain-related behaviour in female C57BL/6 mice
Unpacking the burden: Understanding the relationships between chronic pain and comorbidity in the general population

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Topical Review

Estimate at your peril: Imputation methods for patient withdrawal can bias efficacy outcomes in chronic pain trials using responder analyses

No pain no gain? Pursuing a competing goal inhibits avoidance behavior
02 February 2012
Stefaan Van Damme, Dimitri M.L. Van Ryckeghem, Fran Wyffels, Lore Van Hulle, Geert Crombez
Summary: Pursuing valuable goals reduces pain-related avoidance behavior and the relation between fear and avoidance. This shows the need for a dynamic, contextual-motivational view on disability.Abst...
Calcium/calmodulin dependent kinase II contributes to persistent central neuropathic pain following spinal cord injury
01 February 2012
Eric D. Crown, Young S. Gwak, Zaiming Ye, Huai Yu Tan, Kathia M. Johnson, Guo-Ying Xu, David J. McAdoo, Claire E. Hulsebosch
Summary: Activated neuronal CaMKII is a critical component of the intracellular signaling pathways that contribute to neuropathic pain and persistent neuronal hyperexcitability after spinal cord injur...
Is there a potential role for attention bias modification in pain patients? Results of 2 randomised, controlled trials
27 January 2012
Louise Sharpe, Melissa Ianiello, Blake F. Dear, Kathryn Nicholson Perry, Kathryn Refshauge, Michael K. Nicholas
Summary: Attention bias modification resulted in positive outcomes compared to placebo in 2 randomised, controlled trials in patients with acute and chronic pain.Abstract: Potential applications of at...
Dependence scores predict prognosis of medication overuse headache: a prospective cohort from the Akershus study of chronic headache
27 January 2012
Christofer Lundqvist, Ragnhild Berling Grande, Kjersti Aaseth, Michael Bjørn Russell
Summary: Prognosis regarding out-patient detoxification from medication overuse and improvement of chronic headache is predicted by Severity of Dependence Scale scores in subjects with medication over...
Insomnia, sleep quality, pain, and somatic symptoms: sex differences and shared genetic components
25 January 2012
Jihui Zhang, Siu-Ping Lam, S.X. Li, N.L. Tang, M.W.M. Yu, A.M. Li, Yun-Kwok Wing
TOC summary: A shared genetic predisposition might underlie the associations of insomnia and sleep quality with pain and somatic symptoms. Insomnia seems to modulate the sex differences in pain and so...

View More Articles in Press...

A new definition of neuropathic pain
October 2011 (Vol. 152 | No. 10 | Pages 2204-2205)
Troels S. Jensen, Ralf Baron, Maija Haanpää, Eija Kalso, John D. Loeser, Andrew S.C. Rice, Rolf-Detlef Treede
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NeuPSIG guidelines on neuropathic pain assessment
January 2011 (Vol. 152 | No. 1 | Pages 14-27)
Maija Haanpää, Nadine Attal, Miroslav Backonja, Ralf Baron, Michael Bennett, Didier Bouhassira, Giorgio Cruccu, Per Hansson, Jennifer A. Haythornthwaite, Gian Domenico Iannetti, Troels S. Jensen, Timo Kauppila, Turo J. Nurmikko, Andew S.C. Rice, Michael Rowbotham, Jordi Serra, Claudia Sommer, Blair H. Smith, Rolf-Detlef Treede
Nontricyclic antidepressant analgesics and pain: Are serotonin norepinephrine reuptake inhibitors (SNRIs) any better?
October 2011 (Vol. 152 | No. 10 | Pages 2206-2210)
C. Peter N. Watson, Ian Gilron, Jana Sawynok, Mary E. Lynch
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Considerations for extrapolating evidence of acute and chronic pain analgesic efficacy
August 2011 (Vol. 152 | No. 8 | Pages 1705-1708)
Robert H. Dworkin, Dennis C. Turk, Ethan Basch, Ann Berger, Charles Cleeland, John T. Farrar, Jennifer A. Haythornthwaite, Mark P. Jensen, Robert D. Kerns, John Markman, Linda Porter, Srinivasa N. Raja, Edgar Ross, Knox Todd, Mark Wallace, Clifford J. Woolf
- Full Text
- PDF (119 KB)
Lessons to be learned from placebo groups in clinical trials
August 2011 (Vol. 152 | No. 8 | Pages 1693-1694)
Winfried Rief
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- PDF (75 KB)

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PAIN is the official journal of The International Association for the Study of Pain® (IASP)). IASP publishes PAIN monthly and each issue includes original research on the nature, mechanisms, and treatment of pain. This peer-reviewed journal provides a forum for the dissemination of research in the basic and clinical sciences of multidisciplinary interest and is cited in Current Contents and Index Medicus.

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